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Our Lady of Guadalupe, Original Tilma Reproduction of the original image of Our Lady of Guadalupe on Don Diego's tilma on the Hill of Tepeyec, Mexico. Saint of the Americas and Philippines. She is the Virgin of Guadalupe Nuestra Senora de Guadalupe. Patroness of the Americas, Empress of Latin America, and Protectress of Unborn Children. Original is in the Basilica of Our Lady of Guadalupe near Mexico City and it is the most visited Catholic shrine in the whole world.