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Oh, the joy of prednisone. If you're on, or know someone who's on prednisone, you're probably a little too familiar with the many oh-so-fun side effects of the drug. Increased appetite, aggression, insomnia, and sudden crying....just to name a few. Yep, it's a regular emotional roller coaster. Make sure you warn those around you with this shirt. They'll thank you later.